Abstract: Innovative development of proprietary Chinese medicines is of great value in meeting people's health needs and promoting the development of China's pharmaceutical economy. The innovative development of proprietary Chinese medicines must not only have the theoretical guidance of medicines， but also meet the basic requirements of modern pharmaceuticals. The composition is clear， the quality is stable， the efficacy is clear， and it is developing in the direction of digitization， standardization and modernization. At the same time， there must be theoretical guidance from Chinese medicine. TCM thinking， based on the comparative advantages of Chinese medicine， to meet clinical needs. The clinical needs of Chinese medicine can be divided into two aspects: treating the disease and treating the disease. In the treatment of untreated diseases， physical fitness can be adjusted to improve sub-health， to regulate chronic diseases and prevent mutations， and to protect the epidemic from stagnation and evil spirits; in the treatment of existing diseases， the focus can be on conquering psychosomatic diseases， critical illness and bacterial resistance.