Abstract: Professor Jin Shi believes that wind， phlegm， blood stasis and toxin are the main pathological factors of epileptic seizures associated with systemic lupus erythematosus with central nerve damage， and it is commonly used to add and subtract Dingxian decoction. Patients with central nervous system damage characterized by paroxysmal headache should cooperate with the prescription of Huoxue Dingtong decoction. If the symptoms of central nervous system damage are not serious， the specimen should be treated together and treated with Dingxian decoction and Langchuang formula， which benefits kidney and resolve toxin.