Abstract: OBJECTIVE To research and establish the full wavelength fusion fingerprint of the brown sugar for pharmaceutical excipient. METHODS With a Durashell C₁₈-AM column(4.6 mm×250 mm，5 μm，100 A)，gradient elution was performed by the mobile phase acetonitrile(A)-0.1% trifluoroacetic acid solution(B) at the flow rate of 1.0 mL/min. The column temperature was kept at 25 ℃.The detecting condition was performed with the photodiode array detector at the full wavelength from 210 nm to 400 nm. The data was fused by Waters Empower Chromatography Data Software and analysed with the similarity evaluation system for chromatographic fingerprint of chinese medicine. RESULTS There are 10 common peaks which were founded from fingerprints by similarity analysis， in the 35 batches of brown sugar for pharmaceutical excipient.The fingerprints provided credible similarities of brown sugars for pharmaceutical excipient which were greater than 0.9. CONCLUSION This method which is stable and accurate with good repeatability provides the basis for controlling the fingerprint of brown sugar for pharmaceutical excipient.