隔药灸神阙八阵穴联合生长抑素治疗术后早期炎性肠梗阻的临床研究
Clinical Study on Effect of Medicine Separated Moxibustion on Shenque Eight Point Array Combined with Somatostatin in the Treatment of Early Postoperative Inflammatory Intestinal Obstruction
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摘要: 目的 观察隔药灸神阙八阵穴联合生长抑素治疗术后早期炎性肠梗阻(EPII)的临床疗效。方法 将患者76例患者分为治疗组和对照组，每组38例，2组均接受常规护理及治疗。对照组接受生长抑素（0.25 mg/h连续滴注）治疗；治疗组在对照组的基础上给予隔药灸神阙八阵穴治疗。治疗7 d后，观察主要症状、肠功能情况、血清C反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）水平，统计临床疗效。结果 治疗组和对照组临床疗效的总有效率分别为92.11%、78.95%，P<0.05。治疗后治疗组肠功能情况、血清CRP、TNF-α、IL-6水平均低于对照组，P<0.01。结论 隔药灸神阙八阵穴联合生长抑素能明显改善术后EPII患者的临床症状，与调节血清CRP、TNF-α、IL-6水平有关。Abstract: OBJECTIVE To observe the clinical effect of medicine separated moxibustion on shenque eight-point array combined with somatostatin in the treatment of early postoperative inflammatory intestinal obstruction (EPII). METHODS 76 patients were divided into the treatment group and the control group， 38 cases in each group. Both groups received routine nursing and treatment. The control group was treated with somatostatin (continuous infusion at 0.25 mg/h). On the basis of the control group， the treatment group was also given medicine separated moxibustion on shenque eight-point array. Main symptoms， intestinal function， serum C reactive protein (CRP)， tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) levels were observed after 7 d of treatment， and the clinical effects were recorded. RESULTS The total clinical effective rates in the treatment group and the control group were 92.11% and 78.95%， respectively， P<0.05. Intestinal function， serum CRP， TNF-α and IL-6 levels of the treatment group were lower than those of the control group after the treatment， P<0.01. CONCLUSIONS Medicine separated moxibustion on eight-point array combined with somatostatin can significantly improve postoperative clinical symptoms of EPII patients， and effectively regulate serum CRP， TNF-α and IL-6 levels.
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