Abstract: On the basis of febrile disease cases in Wucun Jingyao， this paper analyzes Ma's experience and therapeutic thoughts for treating damp and febrile disease form four aspects including tracing the etiology and pathogenesis from disease name， syndrome differentiation and treatment and prescriptions applications. According to damp and febrile disease affected easily season， region and population， Ma combined several syndrome differentiations such as wei-qi-ying-blood syndrome differentiation， six-meridian syndrome differentiation and zang-fu syndrome differentiation. His treating method is mainly focus on pungent-bitter， pungent， pungent-warm， aromatic and infiltration. Ma usually uses mild herbs， makes flexible use of fresh herbs， and is good at applying powders and prescribed herbs in decoction. His prescriptions are aiming at regulating qi activities， smoothing sanjiao， reinforcing healthy qi and resisting the external evils attacking the internal. His syndrome differentiation thoughts， prescription applications and combinations have a certain reference and guiding significance for modern clinic， especially for typhoid Salmonella infection and some similar symptoms of enterovirus infections.