Abstract: OBJECTIVE To excavate and analyze 150 ancient acupuncture classics from Tang Dynasty to Qing Dynasty by data mining technology， and summarize points selection characteristics of acupuncture prescriptions for stroke in different dynasties. METHODS Standard library and ancient classics library were set up firstly. Then extract the related statements from classics that corresponding with symptoms， points， meridians， needling and moxibustion methods of stoke， and to form the related library about symptoms， points， meridians， needling and moxibustion methods. The prescriptions were divided into two categories including prescriptions for stroke and prescriptions that mainly containing points for stoke， which were reviewed and standardized manually. Multilevel analysis of acupuncture prescription rules for stroke in different dynasties were realized through statistical analysis and support and confidence of association rules. RESULTS A total of 536 acupuncture and moxibustion prescriptions for stroke were obtained. The use frequency of Baihui points (GV20) was the highest in all dynasties. The compatibility of Baihui(GV20) and Quchi(LI11) was used most frequently in Song， Ming and Qing Dynasties. The compatibility of Dicang (ST4) and Jiache (ST6) was used most frequently in Yuan Dynasty. For meridians selections， apart from the hand jueyin pericardium meridian was selected as yin meridian in Qing Dynasty， the first five meridians in all other dynasties were yang meridians. The governor vessel and the foot shaoyang gallbladder meridian were the most frequently selected meridians in Song and Yuan Dynasties. The hand taiyang large intestine meridian was the most frequently selected meridian Ming and Qing Dynasty. In all dynasties， the support of hand taiyang large intestine meridian and the foot shaoyang gallbladder meridian were the highest. The confluence points were the first selection among specific points， except Qing Dynasty， the compatibility of the confluence points and he-sea points was used most frequently. CONCLUSION In acupuncture and moxibustion classics， the yang convergence Baihui point (GV20) is the first selection in the treatment of stroke. The application of yang meridians and specific points are valued. The point application is fewer but better in ancient time， while later generations gradually increase the number of points.