Abstract: OBJECTIVE To observe antithrombotic effects of panax notoginseng saponins plus aspirin via applying thromboela-stogram(TEG). METHODS 51 patients with senile coronary heart disease were randomly divided into treatment group and control group， with patients in the control group being given aspirin while whose in the treatment group being treated with Sanqi Tongshu Capsule and aspirin. TEG of both groups were observed together with platelet inhibition rate(AA%) induced by arachidonic acid. There existed a statistical significance between the two groups in improving R value， K value and alpha Angle(P<0.05~0.01). RESULTS Reducing scores on SDRS and HAMA of the treatment group before and after treatment were evidently higher than those of the control group(P<0.01). Both groups were effective in improving PSG parameters including sleeping time， sleep latency and sleep efficiency after treatment(P<0.05)， but the treatment group was superior to the control group(P<0.05). The total curative rate of treatment group and control group were 84.85% and 67.74% respectively with a statistical significance between the two groups(P<0.05). CONCULSION Panax notoginseng saponins plus aspirin is superior to aspirin in anti-thrombosis， without increasing the side effects.