Abstract: The concept of lasting movement permeates into many aspects of TCM， has a profound impact on the construction of TCM theoretical system and becomes the driving force of pushing forward the development of the discipline to guide the clinical practice. The concept in Essentials from the Golden Cabinet mainly manifests in disease transformation， disease diagnosis， therapy and medication. The principle is good for the comprehensive and accurate diagnosis of diseases and treatment based on syndrome differentiation so as to improve clinical efficacy.