Abstract: Modern medicine considers breast cancer to be a chronic systemic disease， of which luminal type breast cancer accounts for over 50% of the total cases of breast cancer. While given standardized endocrine therapy， patients with this kind of disease suffered from major side effects such as adverse reactions， poor compliance， tending to drug resistance and long-term recurrence and metastasis. In response to these difficulties， it can be intervened and treated by traditional Chinese medicine. Numerous clinical studies and experimental research results have shown that traditional Chinese medicine has significant effects on the prevention of multiple adverse reactions caused by endocrine therapy， including improving drug resistance， enhancing patients' compliance and reducing long-term recurrence and metastasis risk.