Abstract: This paper held that patients with Sjogren's syndrome should be treated with tonifying kidney through summarizing relevant theories in the Yellow Emperor's Inner Classic. The function of kidney is closely related to the formation of essence， blood and fluid. The pathogenesis of Sjogren's syndrome is either yang deficiency and depression， dysfunction of body fluid， organ dystrophy or essence deficiency and kidney dryness. Therefore， they should be treated respectively: The former one should be treated by moistening dryness with acrid medicinals or resolving constraint with acrid-cool medicinals. The later one should be nourishing kidney and replenishing essence， tonifying blood and reinforcing fluid.