Abstract: OBJECTIVE To observe the clinical effect of Chinese medicine wet compress in the intervention of diabetic foot ulcers of meridians and collaterals heat-stasis accumulation type after interventional vascular surgery. METHODS 57 patients with diabetic foot ulcers were randomly divided into the treatment group (29 cases) and the control group (28 cases). Both groups were given arterial interventional therapy of lower extremity and the basic treatment. On the basis of the control group， the treatment group was also given Chinese medicine wet compress treatment. The clinical effect was observed after 8 weeks of treatment. RESULTS The total effective rate of the treatment group and the control group was 93.10% and 78.57% respectively， the treatment group was better than the control group (P<0.05). After the interventional vascular surgery， the ankle-brachial indexes (ABI) in both groups were significantly decreased than those of the pre-treatment(P<0.01)， and P>0.05 compared between groups. TCM syndrome scores in both groups were improved after the treatment (P<0.01)， and the treatment group was improved more significant than the control group (P<0.01). The wound area and wound volume of the two groups were significantly decreased than those of the pre-treatment (P<0.01)， the treatment group was improved more significant than the control group (P<0.05). After the treatment， the wound healing rate of the treatment group was better than that of the control group compared between two groups (P<0.05). CONCLUSIONS After the interventional vascular surgery， blood supply state of diabetic foot ulcers patients is improved， but the wound can be further healed through combining Chinese medicine wet compress. The effect of the combination treatment is better than interventional vascular surgery only.