Abstract: From the aspects of drug composition， disease syndrome， etiology， pathogenesis and action sites， the prescriptions of Fuling (Poria) and Baizhu (Rhizoma atractylodis macrocephalae) (referred to as Lingzhu Formula) in Treatise on Cold Damage and Essentials from the Golden Cabinet were compared and combed. It is believed that the main treatment of Lingzhu Formula is a type of disease syndrome with abnormal water and liquid metabolism. According to the different positions of fluid retention， the composition of Lingzhu Formula is also different: If the fluid retention accumulated in the head， use Guizhi (Ramulus cinnamomi) Decoction removes Guizhi and add Fuling Baizhu Decoction. If the fluid retention accumulated in the epigastic， chest and rib-side， then use Linggui Zhugan Decotion， Fuling Zexie Decoction. If the fluid retention accumulated in the diaphragm， use Zhuling Powder; in the waist and abdomen， use Ganjiang Lingzhu Decoction; in the exterior and interior， use Wuling Powder. In addition， if the patient with yang deficiency and cold syndrome， it can use Zhenwu Decoction， Fuzi Decoction; with qi deficiency， use Lizhong and Fuling Decoction; with blood stasis， use Danggui Shaoyao Powder.