Abstract: Zhang zhongjing's different prescriptions on the treatment of cold， heat， deficiency and excess syndromes are summarized in the paper. For example， heat syndromes are treated by Pulsatilla decoction and Scutellaria decoction; excess heat is treated by Da Chengqi Decoction or Xiao Chengqi Decoction; cold syndromes are treated by Sili decotion; deficiency syndromes are treated by the Lizhong pill or Halloysite Limonitum decotion .Through the analysis of the above formulas together with clinical experiences， the compatibility rules are summarized for clinical reference.