Abstract: Delphi was thought to be an important method in developing the clinical practice guidelines(CPG) of evidence-based in Traditional Chinese Medicine(TCM) by researching the methodology of developing CPG of TCM. This paper discussed the position and function， specific application and may involve aspects of Delphi in developing CPG of TCM， and pointed out some problems on the development of clinical practice guidelines by using Delphi in evidence-based TCM.