Abstract: OBJECTIVE To observe the clinical efficacy of the basic clearing lung and eliminating phlegm prescription treating on the acute exacerbation phlegm-heat obstructing lung syndrome of COPD， and the influence on the pulmonary function and carbon dioxide retention. METHODS 64 cases， which were chose according the selected standard， were even-randomly divided into treatment group and control group. The control group were given western conventional therapy， and on the base， treatment group were add Qingfei Huatan Granule(a kind of TCM granule without decoct)， and 2 weeks were one course. Then compare the clinical syndrome， lung function and blood gas analysis. RESULTS The treatment group are better than the control group on treating the clinical syndrome， physical sign， lung function and carbon dioxide retention(P<0.05). CONCLUSION Qingfei Huatan Granule has a good effect on treating the phlegm-heat obstructing lung syndrome of COPD. The prescription can improve the clinical symptoms and lung function， relieve the carbon dioxide retention and improve the quality of life.