Abstract: OBJECTIVE To observe the clinical efficacy of Jujing Pill in treating oligospermia or asthenospermia. METHODS 125 cases of the oligospermia or asthenospermia patients were divided into control group (40 cases) and treatment group (85cases) at random. The control group took Vit E twice a day and 100 mg each time. The treatment group were treated by Jujing Pill one dose a day. The semen volume， semen density， a and b grade sperms， total motility rate and pregnant rate of the two groups were tested 6 months before and after treatment. RESULTS 125 patients all finished the treatment. Both two groups can increase patients' semen volume， a standard sperms， forward moving sperms and total motility rate (P<0.05). The treatment group could also improve the patients' semen density remarkably (P<0.05) and was superior to control group in the improvement of semen density， a grade sperms and forward moving sperms， total motility rate and pregnant rate (P<0.05). CONCLUTION Jujing Pill can significantly improve the semen quality of the oligospermia or asthenospermia patients and be used to treat sterility.