Abstract: OBJECTIVE To evaluate the benefits and side effects of moxibustion therapy for coronary artery disease. METHODS Relevant studies of moxibustion therapy for angina were collected from databases including Pubmed， Embase，Cochrane library， CNKI， Wanfang Database and CBMDisk. The inclusion and exclusion criteria was applied when the literature was screened， data was extracted and the quality of the included studies were assessed independently. Then， meta-analysis was performed by using RevMan 5.2 software. RESULTS 1 318 patients and 13 researches about moxibustion therapy for coronary artery disease were collected. The Meta analysis showed that compared with the control group， the western medicine groupRR=1.22，95%CI(1.11，1.33)and the acupuncture groupRR=1.5，95%CI(1.23，1.83)， the moxibustion group showed great improvement in relieving angina pectorisis and good effects were shown in the ECGRR=1.23，95%CI(1.14，1.33). In terms of blood liquids， the moxibustion group showed good effects in regulating triglycerideSMD=-0.81，95%CI(-1.57，-0.06)， low density lipoprotein cholesterinSMD =-0.55，95%CI(-1.04，-0.06)， and high density lipoprotein cholesterolSMD=0.43，95%CI(0.2，0.65) and the changes were of statistical significance. Compared with the Chinese medicine group， the improvement in angina pectorisis of the moxibustion group showed no statistical significanceRR=1.15，95%CI(0.99，1.35). The difference between the changes of total cholesterol in the treatment group and the control group had no statistical significanceSMD=-0.74，95%CI(-1.75，0.27). CONCLUSION Moxibustion is a unique TCM therapy in treating angina pectorisis and can be applied in clinical practices. Meanwhile， the outcome of this system was not perfect. And more high quality of randomized controlled trials are needed to verify the effect of the therapy.