结构方程模型探讨慢性萎缩性胃炎证候分型规律
An Investigation into Regularity of Syndrome Classification for Chronic Atrophic Gastritis Based on Structural Equation Model
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摘要: 目的采用结构方程模型探讨西医病名慢性萎缩性胃炎的中医证候分型规律。方法采用临床流行病学的方法采集慢性萎缩性胃炎病人的中医四诊信息和胃镜病理特征资料,根据病例特征的多维指标和中医先验理论建立合适的结构方程模型,并拟合和考核模型。结果可接受的模型从202个CAG合格病例的22个辨证相关指标,抽取了4个潜在因变量,分别对应于中医的4个常见证型:脾胃湿热证、肝胃不和证、脾胃虚弱证和胃阴不足证,并与相应的显性四诊信息相关,4个潜在因变量都受一个潜在自变量影响,而潜在自变量反映了CAG疾病的共有性质。结论CAG的最常见中医证型有4个,并分别与相应的辨证指标相联系,其联系的强弱有差别;本次研究中,公有症状主要为胃脘痛和纳差,基本符合中医临床实际;SEM分析表明,该方法用于解释特定疾病下的中医证的存在和测量方法是可行的。Abstract: OBJECTIVE To investigate into the regularity of syndrome classification for chronic atrophic gastritis(CAG) using structural equation model(SEM).METHOD Epidemiological method was adopted to collect the information of the CAG patients based on the four diagnostic method and data of the pathological features of the disease based on gastroscope examination.Structural equation models were built by means of multidimensional indexes of disease feature and apriorism.RESULT Among the 22 indexes of syndrome differentiation,4 potential dependent variables were extracted,corresponding respectively to the four common syndromes: damp heat of the spleen and stomach,incoordination between the liver and stomach,deficiency of the spleen and stomach and deficiency of stomach yin,which were respectively correlated to the information of dominant four diagnostic methods.Each of the four dependent variables was affected by a potential independent variable,which reflected the common property of CAG.CONCLUSION There are four most common CAG syndromes correlated to the corresponding syndrome differentiation indexes,with differences in the intensity of their correlation.In this study,the common symptoms are epigastric pain and poor appetite,which conforms to the reality of TCM clinical practice.SEM analysis shows that this method is practical in the explanation of the presence of TCM syndromes of specific diseases and the method of their measurement.
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Keywords:
- SEM /
- chronic atrophic gastritis /
- TCM syndromes /
- analytical technology
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