Abstract: OBJECTIVE To optimize the alcohol extraction techniques of the medicinal herbs such as Rhizoma Corydalis Yanhusuo in Compound Tongsuxiao Drop Pill.METHOD Orthogonal method was used to optimize the alcohol extraction techniques,with the soft extract derivation rate and the content of corydalis B and ammidin as the indexes.RESULT The optimized extraction technique is the following: grind the medicinal material into powder soaked in 80% alcohol six times in amount for 12 hours,followed by extraction with the percolation method.CONCLUSION The optimized technique is workable.