Abstract: This paper explores the pathogenesis and treatment methods of acupuncture and moxibustion intervention for drug-dependent insomnia. It argues that treatment faces the dual challenges of drug tolerance and withdrawal reactions. Based on this, an intervention system of sequential acupuncture and moxibustion-based medication reduction therapy is constructed. By establishing a three-stage diagnostic and treatment pathway—maintaining drug efficacy, stepwise medication reduction, and efficacy consolidation—combined with an internet-based traditional Chinese medicine sleep management platform for dynamic sleep monitoring, this therapeutic regimen employs principal acupoint combinations based on the unblocking the Governor Vessel and regulating spirit needling technique alongside personalized auxiliary point selections. It demonstrates efficacy in improving sleep quality, facilitating gradual medication reduction, and exhibits distinctive advantages in mitigating withdrawal symptoms and reducing relapse rates. The diagnostic and therapeutic rationale provides valuable insights for clinical management of chronic insomnia with comorbid drug dependence.