基于文献计量学探析桔梗汤研究的演进、热点及展望

Analysis on the Evolution, Hot Spots and Prospects of Jiegeng Decoction Research Based on Bibliometrics

  • 摘要:
    目的 从文献计量学角度系统分析桔梗汤的研究现状与热点,为其临床应用与深入研究提供理论参考。
    方法 检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)数据库中至2025年3月的相关文献,使用NoteExpress进行去重筛选,结合Excel、CiteSpace和VOSviewer对发文趋势、国家/机构合作、作者网络及关键词等维度进行可视化分析。
    结果 共纳入中文文献597篇,发文量呈四阶段演变特征,核心研究机构集中于中医药院校及其附属医院,跨区域合作较少。文献聚焦桔梗汤的“咳嗽”“治疗”“慢性咽炎”等方向。突现关键词显示,“作用机制”“疗效”“用药规律”“抗病毒”等为近年新兴热点。
    结论 桔梗汤研究正从单一病症治疗转向多靶点系统调控,未来需加强跨学科整合,深化桔梗汤在呼吸道病毒性感染中的免疫调节机制研究,构建“化学成分-生物效应”关联质控体系,深化网络药理学与临床应用情况研究结合,为经典方剂的现代化提供新范式。

     

    Abstract:
    OBJECTIVE To systematically analyse the research status and hotspots of Jiegeng decoction from the perspective of bibliometrics, and to provide theoretical references for its clinical application and in-depth research.
    METHODS We searched the relevant literature in the databases of China Knowledge Network (CNKI), Wanfang and VIP up to March 2025, and used NoteExpress for de-duplication and screening, combined with Excel, CiteSpace, and VOSviewer to analyse the dimensions of trend of issuance, country/institution cooperation, author network, and keywords. The dimensions of publication trend, country/institution collaboration, author network and keywords were visualised and analysed by combining Excel, CiteSpace and VOSviewer.
    RESULTS A total of 597 Chinese articles were included. The number of variable publications was characterised by a four-stage evolution, with the core research institutions focusing on TCM colleges and affiliated hospitals, and less cross-country collaboration. Literature focused on the effects of Jiegeng decoction on "cough", "treatment" and "chronic pharyngitis". Emerging keywords indicated that "mechanism of action", "therapeutic effect", "medication pattern" and "antiviral" were emerging hot topics in recent years.
    CONCLUSION The study of Jiegeng decoction is shifting from single disease treatment to multi-target system regulation. In the future, it is necessary to strengthen the interdisciplinary integration, deepen the research on the immunomodulatory mechanism of Jiegeng decoction in respiratory viral infections, build the "chemical component-biological effect" related quality control system, deepen the combination of network pharmacology and real-world research, and provide a new paradigm for the modernisation of classical prescriptions.

     

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