易筋经对老年肌少症患者肌肉力量及慢性炎症的影响

Effect of Yijinjing on Muscle Strength and Chronic Inflammation in Elderly Patients with Sarcopenia

  • 摘要:
    目的 观察易筋经治疗老年肌少症的临床疗效及对患者慢性炎症反应的影响,探究适合老年肌少症患者的易筋经运动功法处方。
    方法 选取苏州市中医医院康复医学科2022年9月至2024年9月的老年肌少症患者120例,采用随机数字表法分为对照组和易筋经组各60例。对照组予健康教育和饮食指导,易筋经组在对照组干预基础上予易筋经功法锻炼。干预前后观察2组患者骨骼肌质量指数、肌肉握力、30 s坐立试验次数、肌肉厚度和横截面积、SPPB评分和血清中肿瘤坏死因子(TNF)-α、白细胞介素(IL)-6、IL-18表达水平。
    结果 干预后,易筋经组骨骼肌质量指数、肌肉握力、30 s坐立试验次数、SPPB评分、股直肌厚度和横截面积、股中间肌厚度、血清TNF-α和IL-18水平较干预前升高(P < 0.05,P < 0.01),优于对照组(P < 0.05,P < 0.01);易筋经干预后TNF-α水平与握力呈显著性负相关,r=-0.313 8,P < 0.05。
    结论 易筋经功法训练可以提高老年肌少症患者肌肉质量和肌力,提高患者体能水平,可能与改善机体慢性炎性状态有关。

     

    Abstract:
    OBJECTIVE To observe the clinical efficacy of Yijinjing in the treatment of elderly sarcopenia and its effect on chronic inflammatory response in patients, and to explore the Yijinjing exercise prescription suitable for elderly patients with sarcopenia.
    METHODS A total of 120 elderly patients with sarcopenia admitted to the Department of Rehabilitation Medicine, Suzhou Hospital of Traditional Chinese Medicine from September 2022 to September 2024 were selected and randomly divided into a control group and a Yijinjing group, with 60 cases in each group. The control group received health education and dietary guidance, and the Yijinjing group received Yijinjing exercises on the basis of the intervention of the control group. The changes in skeletal muscle mass, upper and lower limb muscle strength, muscle thickness, muscle cross-sectional area, physical fitness and chronic inflammation level were observed in the two groups before and after the intervention.
    RESULTS After intervention, the skeletal muscle mass, grip strength, 30 s sit-stand test times, rectus femoris thickness and cross-sectional area, vastus intermedius thickness, and physical fitness assessment of the patients in the Yijinjing group were significantly increased compared with those before treatment (P < 0.05), and the indicators after intervention were higher than those in the control group (P < 0.05); the serum TNF-α and IL-18 levels in the Yijinjing group were significantly decreased compared with those before treatment (P < 0.05), and the indicators after intervention were lower than those in the control group (P < 0.05); there was no statistically significant change in the biceps brachii thickness and serum IL-6 level in the Yijinjing group compared with those before treatment (P>0.05); there was no significant correlation between the biceps brachii thickness and grip strength after Yijinjing intervention, r=0.139 8, P>0.05; there was a significant negative correlation between the TNF-α level and grip strength after Yijinjing intervention, r=-0. 313 8, P < 0.05.
    CONCLUSION Yijinjing exercises can improve muscle mass and strength in elderly patients with sarcopenia, and improve the physical fitness of patients, which may be related to improving the chronic inflammatory state of the body.

     

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