Abstract: Professor Zou Yunxiang proposed the "kidney essence theory" in 1955, which believes that the kidney, as an important excretory organ in the human body, participates in the body's metabolism, and the basis for producing this effect is the essence of the kidney. Subsequently, the Zou nephrology team established the core medical technique of "tonifying the kidney element" based on this foundation, constructed a system of syndrome differentiation and treatment for chronic kidney disease, proposed the traditional Chinese medicine names, causes, and mechanisms of chronic kidney disease, as well as four major methods for diagnosing and treating chronic kidney disease, and developed representative drugs representing the core medical technique of "tonifying the kidney element" - Huangzhi Yishen Capsules and Shenwu Yishen Tablets. In addition, the Zou nephrology team has extensively applied and promoted the core medical technique of "tonifying the kidney element".