Abstract: Chinese medicine and Western medicine are two independent medical systems and diagnosis and treatment models. In the current emphasis on comprehensive treatment of tumors, exploring and constructing a new model of integrated Chinese and Western medicine for tumor diagnosis and treatment is of great significance. Chinese medicine emphasizes the overall view and prevents diseases in the treatment of tumors. It has the advantages of regulating the body as a whole, achieving survival with tumors, and preventing recurrence and metastasis. However, in the context of modern medicine, it faces problems such as unclear diagnosis, imprecise treatment, uncertain efficacy, and unclear mechanism. In order to effectively improve the clinical efficacy of tumor treatment, this paper proposes the diagnosis and treatment ideas of "disease-stage-pathogenesis-syndrome-target" based on the characteristics and advantages of Chinese medicine and combined with the research results of modern medicine, and preliminarily constructs a new model of tumor diagnosis and treatment combining Chinese and Western medicine, in order to achieve complementary advantages and synergistic effects of Chinese and Western medicine.