Abstract: This article summarizes Professor Xu Zhiyin's experience in treating non-puerperal mastitis from the perspective of middle jiao qi movement and believes that the pathological viscera of non-puerperal mastitis are located in the liver, spleen, and stomach, and closely related to the middle jiao qi movement. According to clinical manifestations, the disease can be divided into lump stage, abscess stage, and fistula stage. The main pathogenesis of the disease is liver depression-spleen deficiency and phlegm obstructing the breast collaterals; long-term heat stagnation and excessive heat corroding the flesh; qi deficiency-evil stagnation and lingering restraining. In terms of treatment, the pathogenesis should be clearly identified according to the different stages of the disease, and the medicine should be changed according to the pathogenesis. The key of treatment is to regulate the middle jiao qi movement and adjust the treatment according to the stage. In the lump stage, use pungency to disperse and bitterness to descend, and suppress wood and support soil; in the abscess stage, lower the turbidity and raise the clearness, and discharge the fire and calm the wood; in the fistula stage, mobilize the central prefecture, and cultivate the soil and nourish the wood, so as to obtain satisfactory curative effect.