Abstract: Fritillaria ussuriensis is a valuable traditional Chinese medicine in cold regions, which has the functions of dispersing stagnation and relieving depression, moistening lung and clearing heart. It is widely used in the treatment of diseases such as qi adverseness and cough, pharyngitis, sore and carbuncle, etc. Whether it is used alone or in combination, it has good results. It is a pure natural and efficient drug with broad development prospects. In recent years, with the deepening of research on Fritillaria ussuriensis, alkaloids, nucleosides, polysaccharides, volatile oils, organic acids and other components have been isolated.It has pharmacological activities such as relieving asthma, relieving cough, expectorant, calming, anti-inflammatory and antibacterial. By reviewing the reports of chemical constituents and pharmacological effects of Fritillaria ussuriensis in the past 40 years, this paper systematically summarizes and analyzes the research results in order to provide scientific basis for the study of pharmacodynamic substance basis and promote the development and utilization of Fritillaria ussuriensis.