Abstract: The article summarizes Professor Huang Chunlin's experience in treating IgA nephropathy with the theory of "correlation between the five viscera" and proposes that although the disease location of IgA nephropathy is mainly in the kidney and bladder, it is closely related to the lungs, spleen, heart, liver and other organs. The etiology and pathogenesis can be summarized into two aspects: external infection and internal injury, among which external infection is often caused by pathogenic toxins such as wind, heat, and dampness invading the human body; internal injuries are often attributed to dysfunction of viscera. The core of the pathogenesis is that the kidney qi is not solid, the yin and yang in the kidney are out of balance, and the movement of qi is abnormally ascending and descending, which can easily lead to external and internal pathogenic factors. The excess of evil qi along the meridians can affect the kidney meridians, resulting in powerlessness in constraint, overflow of essence and blood, leading to IgA nephropathy. The treatment should start from a holistic perspective of "kidney-based and five-viscera-related", and be dialectical based on the onset, progression, refractory factors and complications that affect IgA nephropathy.