Abstract: Based on the modern theory of psychological stress and emotional pathogenesis in traditional Chinese medicine, this paper analyzes the mechanism of recurrent spontaneous abortion (RSA) caused by emotional factors. Studies have found that the biological mechanism of RSA caused by emotional factors such as psychological stress includes endocrine system, central nervous system, oxidative stress, immune defense and other aspects; spleen and kidney deficiency caused by mental disturbance and liver qi stagnation are the TCM pathogenesis of RSA caused by emotional factors, and the diagnosis and treatment ideas of treating from the heart, treating from the liver and TCM emotional therapy are proposed.