Abstract: Medicine and food homologous traditional Chinese medicine (MFHTCM) is a type of Chinese medicinal material resource that has been gradually discovered by humans in long-term production and life practice, which combines the characteristics of both medicine and food. It is an important material foundation for the construction of a healthy China and the development of the big health industry. On the basis of summarizing and analyzing the current research status and existing problems in the industrial development process of MFHTCM in recent years, this article proposes a production layout strategy for MFHTCM based on differentiated development of medicinal and edible characteristics, a characterization strategy for MFHTCM efficacy based on modern multi-omics technology, a development strategy for new varieties and new parts of MFHTCM based on the records of Chinese herbal classics and folk application habits, and a MFHTCM development strategy of medicine and food homologous products based on probiotic fermentation technology and modern nutrition theory. All the above aim to provide technological support for promoting the high-value development and utilization of MFHTCM, and to assist in the construction of a healthy China in the new era.