Abstract: Refractory mycoplasma pneumoniae pneumonia (RMPP) is developed from mycoplasma pneumoniae pneumonia (MPP). The incidence rate among children shows a rising trend year by year, and it is likely to be complicated by multiple organ injuries if the course is prolonged. Aiming at the current common clinical problems of RMPP, this paper summarizes the TCM treatment experience and countermeasures to provide a reference for the clinical treatment and research of RMPP.