Abstract: This paper summarized Professor Wang Shou-chuan's clinical experience of differential diagnosis and treatment of vocal tic in children by mediating qi activities of the five internal organs. It is believed that the lesion of vocal tic is located in the throat; the incidence of the disease is linked to the disorder of qi movements of the five internal organs. The pathogenic factors and the mechanism are wind invading the lung, spleen deficiency engendering phlegm, intense heart fire, kidney-yin deficiency, and then, inducing the liver wind. The clinical treatment is guided by the overall concept, with syndrome differentiation of the five internal organs as the main method. The method of soothing the lung, calming the liver, invigorating the spleen, clearing the heart fire and nourishing the kidney-yin can be separately applied in the light of the changes of pathogenesis, thus, the qi activities can be mediated, qi reversed and sound reduced. In order to achieve a better curative effect, pay attention to the children's mood and the clothing they are wearing in relation to temperature changes.