Abstract: Rheumatoid arthritis is a common chronic systemic immune disease. Professor Jin Shi believes that the disease begins with congenital deficiency of kidney essence. After the long course of the disease, the lack of production and transformation source of qi and blood can lead to the poor qi movement and blood circulation. As the condition gets worse, it will breed pathogenic phlegm and stasis. Besides, excessive drug use and physical disability can also exacerbate the disease, which is deficiency in root and excess in manifestation. Bones and collaterals are the delicate structures for running qi and blood, which are often weakened by qi- and blood-deficiency. In addition, they are easily paralyzed by pathogenic phlegm and stasis. The disfunction of bones and collaterals can lead to bone marrow malnutrition, further resulting in bone withering and marrow reduction, and thus leading to osteoporosis. Professor Jin Shi took the deficiency of kidney essence, combined with paralysis and obstruction of bone and collaterals as the core pathogenesis of rheumatoid arthritis with a secondary osteoporosis. Therefore, when the treatment method of benefiting kidney and unblocking the collaterals is applied clinically, a better therapeutic effect can be achieved.