Abstract: "Cancer toxin" is an important factor leading to the occurrence and development of tumors. Cancerous pain is caused by cancer toxin, and the pathological products "phlegm, blood stasis, depression and deficiency" produced in the process of tumor occurrence and development are the main pathological factors of cancerous pain, "cancer toxin" runs through the whole process of cancerous pain. The internal accumulation of cancer toxin and the mutual formation of phlegm and blood stasis are the key to the pathogenesis of cancerous pain. The disease location involves related viscera and meridians. Locally true; detoxification and blood stasis, phlegm and collaterals are the basic treatment methods.