Abstract: In recent years, transdermal administration has been more and more popular because of its simplicity, convenience, efficacy and low cost because it can overcome the shortcomings of gastrointestinal digestive reaction after oral administration, liver first-pass effect, and pain caused by injection administration. more and more people's attention. However, solving the low absorption efficiency of transdermal administration has become a key problem in the research of modern pharmaceutical preparations. By consulting relevant literature, it is found that nanocarriers, new methods of promoting penetration of volatile oils of traditional Chinese medicine, and new technologies of physical penetration provide new ideas for improving the absorption efficiency of transdermal drug delivery; therefore, this paper focuses on summarizing and analyzing the existing In order to provide reference and reference for the new technology and new method of percutaneous permeation promotion for external use.