Abstract: Knowledge graph research is rapidly developing in the field of traditional Chinese medicine (TCM). It has also been applied to many aspects of TCM, such as basic theory, clinical support, as well as prescriptions and medicines. Through reviewing the concept, key technologies and the current status of knowledge graph research in TCM, we summarize the related problems including the unification of TCM terminology standards, the construction of knowledge graph model levels, the regulation of TCM knowledge fusion technology, as well as the design and selection of reasoning methods. In addition, the development trend of knowledge graph research in TCM is prospected. Thus, it is suggested that TCM knowledge graph research should effectively solve the practical problems in clinical situations, strengthen the exploration of knowledge graph construction methods and technologies by combining the characteristics of TCM system itself, and study how to model TCM knowledge more accurately to provide support for the realization of auxiliary decision-making and intelligent question answering services.