Abstract: Zhang Jianzhai's treatment of gynecological diseases is characterized by: Identifying the deficiency and excess together with harmonizing qi and blood in both supplementing and dredging way, benefiting the liver and kidney combined with consolidating the chong and ren mai to regulate and nourish extraordinary vessels, reinforcing the five viscera conjoined with differentiating cold and heat to treat both the exterior and interior. In addition, Zhang Jianzhai pays special attention to the syndrome differentiation of qi and blood, takes into account the aspects of cold and heat, exterior and interior, deficiency and excess, as well as zang-fu organs. His treatment is good at regulating and nourishing extraordinary vessels, applying both tough and gentle therapies, as well as eliminating the excess with light medicine.