Abstract: In recent years, the research and development of TCM classical prescription is a hot spot in the Chinese medicine industry. In order to solve the problem of quality difference between batches of TCM Patent Prescription, the author of this paper elaborate the key factors affecting the quality of TCM classical prescription and the key techniques affecting the quantity value transfer through the level of medicinal material, herbal decoction pieces, Material baseline and preparations, according to the declaration information demand of Material baseline and TCM Patent Prescription.