Abstract: Platycodonis Radix is the dried root of Platycodon grandiflorum (Jacq.) A. DC, which mainly contains saponins, flavonoids, polysaccharides, sterols and fatty acids. Modern studies have shown that Platycodonis Radix has pharmacological effects such as expectant and cough relieving, anti-inflammatory, anti-tumor, hypoglycemic, anti-obesity and immunoregulation.In this paper, the chemical constituents, pharmacological activities, in vivo process, toxicity, hemolysis and quality standard of Platycodonis Radix were systematically reviewed, and the quality markers of Platycodonis Radix were also discussed, in order to provide reference for further research and development of Platycodonis Radix. KEYWORDS: Platycodonis Radix; chemical composition; pharmacological activities; Q-marker