Abstract: The paper discussed the pathogenesis, staging and treatment method of xuefen syndrome in warm diseases. At the initial stage, the pathogenesis was impairment of blood induced by blood heat, as well as combination of stasis and heat, so the treatment principle should be cooling blood and dissipating stasis. When it came to the mid-term, it turned into bleeding due to blood-heat combined with stasis and should be treated with cooling blood and dissipating stasis to stop bleeding. As for the later period, it was qi prostration due to heat and stasis or excessive bleeding followed by exhaustion of vital energy and the treatment aimed to strengthen body resistance and relieving desertion.