Abstract: COVID-19 is thought to be one kind of epidemic diseases in traditional Chinese medicine. Through the discrimination of two clinical cases， the authors thought COVID-19 was characterized by dampness-toxin as the etiology accompanied with cold or heat. Most patients suffered from cold-dampness symptoms at the beginning and then heat-dampness. However， when it came to the patients inborn with dampness-heat constitution， dampness-heat symptoms were the main clinical manifestation at the initial period. It usually attacked human's lung and spleen. Dispelling dampness and resoling toxin was the main therapeutic method. In addition to dissipating cold to eliminate dampness and clearing heat to dispel dampness， there were other applicable methods， such as promoting qi movement， activating blood to dissolve stasis， tonifying spleen to boost qi. What's more， something pungent， warm， soft， moist， cold and cool should all be avoided. Over and above， it was significant to differentiate patients' aversion to cold early in COVID-19 to exterior patterns in cold.