SUNKan-ping, XIELi, QINKun-ming, JINJun-jie, YANGChao, LIUXiao, CAIBao-chang. Influence of Processing on Volatile Components of Baizhu Shaoyao San Based on GC-MS Technique[J]. Journal of Nanjing University of traditional Chinese Medicine, 2020, 36(1): 94-101.
Citation: SUNKan-ping, XIELi, QINKun-ming, JINJun-jie, YANGChao, LIUXiao, CAIBao-chang. Influence of Processing on Volatile Components of Baizhu Shaoyao San Based on GC-MS Technique[J]. Journal of Nanjing University of traditional Chinese Medicine, 2020, 36(1): 94-101.

Influence of Processing on Volatile Components of Baizhu Shaoyao San Based on GC-MS Technique

More Information
  • OBJECTIVE To identify and analyze the chemical composition of the volatile components in Baizhu Shaoyao San (BZSYS), decoction sample composed with unprocessed herbal drugs was tested for a purpose of comparation. METHODS The volatile oil was extracted from BZSYS decoction by steam distillation, diluted and then separated by GC-MS. Components were matched and identified based on NIST 11 and Wiley databases. The relative contents of these components were calculated by normalization method. Finally, the volatile oil samples obtained from processed or unprocessed drugs were compared and analyzed. RESULTS A total of 145 components were matched by data analysis in both groups. After processing, 15 components were found to be disappeared, while 17 new components were found to be appeared. CONCLUSION The processing of herbal drugs shows a significant influence on the volatile components of BZSYS. It is a realistic and objective reason that BZSYS should be composed with processed drugs just as recorded in the ancient literature.
  • [1]
    章宸, 刘斌, 郑虎占, 等. 痛泻要方药理作用和临床应用研究概况[J]. 中国实验方剂学杂志, 2010, 16(7): 223-226.
    [2]
    邱根全, 赵旭升. 白术挥发油治疗癌性恶病质的实验研究[J]. 西安交通大学学报(医学版), 2006, 27(5): 477-479.
    [3]
    孙言才, 沈玉先, 孙国平. 丹皮酚的主要药理活性研究进展[J]. 中成药, 2004, 26(7): 579-582.
    [4]
    徐彭. 陈皮水提物和陈皮挥发油的药理作用比较[J]. 江西中医学院学报, 1998, 10(4): 172-173.
    [5]
    黎建斌, 刘丽萍, 邱振文. 生防风挥发油抗炎止血作用的药理研究[J]. 新中医, 2007, 39(8): 105-106.
    [6]
    钱雷, 时贞平, 郭英球. 推拿配合白术芍药散治疗腹泻型肠易激综合征53例[J]. 中医药导报, 2010, 16(10): 63-64.
    [7]
    朱秋双, 赵玉珍, 张明远, 等. 白术芍药散抗腹泻药效实验研究[J]. 黑龙江医药科学, 2007, 30(1): 25-29.
    [8]
    瞿领航, 涂济源, 曹国胜,等. 基于燥胜则干和燥性伤阴理论的苍术燥性效应研究[J]. 中国中药杂志, 2018, 43(13):123-129.
    [9]
    国家药典委员会. 中国药典:一部[S]. 北京: 中国医药科技出版社, 2015.
    [10]
    国家药典委员会. 中国药典:四部[S]. 北京: 中国医药科技出版社, 2015.
    [11]
    崔庆新, 董岩, 王怀生. 白术挥发油化学成分的GC/MS分析[J]. 药物分析杂志, 2006, 26(1): 124-126.
    [12]
    张丹,牟玉莹. 防风药材及其伪品的挥发油类成分气相指纹图谱研究[J]. 亚太传统医药, 2019, 15(4): 61-63.
    [13]
    龚范, 梁逸曾, 宋又群, 等. 陈皮挥发油的气相色谱/质谱分析[J]. 分析化学, 2000,12(7): 860-864.
    [14]
    瞿白露, 吴泓毅, 任凤莲, 等. GC-MS分析白芍挥发油的成分[J]. 食品科技, 2009, 34(3): 92-95.
    [15]
    杜卉, 张扬, 孟祥健, 等. 棕榈酸对肝细胞自噬和凋亡的影响[J]. 皖南医学院学报, 2019, 38(1): 5-8.
    [16]
    TU QQ, ZHENG RY, LI J, et al. Palmitic acid induces autophagy in hepatocytes via JNK2 activation[J]. Acta Pharmacol Sin, 2014, 35(4):504-512.
    [17]
    郑礼娟. 炮制对白术芍药散化学成分、药动学及药效学影响的研究[D]. 南京:南京中医药大学, 2014.
    [18]
    王小芳, 王芳, 张亚环, 等. 白术挥发油中苍术酮氧化反应的动力学[J]. 应用化学, 2007,22(3): 301-305.
    [19]
    石晓, 黄艳萍. GC-MS分析白术炮制前后化学成分的变化[J]. 食品与药品, 2011, 13(1): 36-38.

Catalog

    Article Metrics

    Article views (793) PDF downloads (423) Cited by()
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return