Meta-Analysis on the Effect of Ventilating Lung Qi for Postinfectious Cough

OBJECTIVE To systematically assess the efficacy and safety of Ventilating Lung Qi for the treatment of postinfectious cough. METHODS All randomized controlled trails (RCT) regarding Ventilating Lung valuation the treatment of Postinfectious cough date up to September 2016 were collected from the Cochrane library， PubMed， china biology medicine (CBM)， CNKI， VIP and Wanfang. Jadad scale was taken for quality evaluation of the included studies by two researches. The patients in the control group were given conventional treatment， the experimental group was given ventilating lung qi treatment or combined with other treatments. The total effective rate， the integral of cough symptoms， cough response time， and the adverse reactions of patients treated with Ventilating Lung Qi method were systematically evaluated by RevMan 5.3 software. RESULTS A total of 33 RCT literatures were enrolled. Meta-analysis results showed that Vantilating Lung Qi method could significantly increase the total effect rate OR=4.10，95%CI（3.25，5.18），P<0.01， in cough treatment， improve integral of cough symptom MD=-1.93，95%CI（-2.59，-1.27），P<0.01， and effectively decrease cough response time MD=-1.09，95%CI(-1.31，-0.87)，P<0.01 compared with those of the conventional treatment. And the adverse reactions in Ventilating Lung Qi group was also significantly lower OR=0.36，95%CI(0.18，0.72)，P<0.01 than that in the control group. CONCLUSION The Ventilating Lung Qi method has obvious advantages for treating postinfectious cough. But， for the low-quality of the enrolled literatures， large-scale， high-quality RC are needed to provide stronger evidence.