Study on Effects of Jianpi Qingchang Formula on the Recurrence of Colorectal Adenomas After Resection

OBJECTIVE To study the effects of Chinese medicine on patients with endoscopic resection of adenomatous colorectal polyps. METHODS 60 adenomatous colorectal polyps patients meeting with the criterion were investigated and randomly divided into two groups， Chinese medicine intervention group and the control group. Same treatments including fasting， anti-inflammation， anti-infection and parenteral nutrition support were performed to all patients after surgery: for 1-3 days. Jianpi Qingchang formula was given to the Chinese medicine intervention group on the 2nd day after surgery， while no more intervention was given to the control group. The recurrence condition of polyps was checked by colonoscopy at 6 months and 12 months after the surgery， respectively. The evaluation criterion was whether there were any new polyps in the original resected sites or other parts. The pathological types were compared and the recurrence rate of the 2 groups were evaluated. RESULTS The bowel evacuation frequency and habit scores of the two groups were compared after 6 months of treatment P<0.05，P<0.01. The number， maximum diameter and average diameter of adenomas of the two groups were compared after 6 months of treatment， P<0.01. After 6 months of follow-up， the total effective rate of the Chinese medicine intervention group was 93.33%， and that of the control group was after 83.33%， there were significant differences between the two groups. After one year of follow-up， the total effective rates of the Chinese medicine intervention group and the control group were 93.33% and 80.00%， respectively， there were significant differences between the two groups， P<0.01. CONCLUSIONS Chinese medicine intervention can reduce the recurrence rate of patients with adenomatous colorectal polys after endoscopic resection surgery.