Clinical Study on Buyang Huanwu Decoction in the Treatment of Coronary Heart Disease Angina Pectoris of Qi Deficiency and Blood Stasis Type

OBJECTIVE To observe the clinical effect of Buyang Huanwu decoction in the treatment of coronary heart disease angina pectoris of qi deficiency and blood stasis type. METHODS Sixty eight patients with coronary heart disease angina pectoris of qi deficiency and blood stasis type treated by Buyang Huanwu decoction were taken as the treatment group， and was compared with the control group (62 cases treated with conventional western medicine). Angina pectoris efficacy， ECG efficacy， angina pectoris symptoms and blood lipid indexes in two groups were compared. RESULTS The total effective rate of chest tightness and breath shortness improvements in the treatment group was 95.6%， which was significantly higher than that in the control group (80.6%，P<0.05). The total effective rate of palpitation improvement in the treatment group was 88.2%， which was significantly higher than that in the control group (77.4%， P<0.05). The total effective rate of angina pectoris in treatment group and control group was 82.35% and 70.97% respectively， and the total effective rate of ECG was 76.5% and 58.06% respectively， the differences between two groups were significant， P<0.05. The angina pectoris attack frequency and duration in the treatment group decreased more significantly in the treatment group compared with the control group (P<0.05). The nitroglycerin reducing and stopping rate in the treatment group was 80.8%， which was significantly higher than that in the control group (51.6%)， P<0.01.The levels of TC， TG， LDL-C， HDL-C， ApoA1， ApoB and LP (a) in the treatment group were statistically significant after treatment compared with the control group (P<0.01).CONCLUSIONS Buyang Huanwu decoction has definite curative effect for treating coronary heart disease angina pectoris of qi deficiency and blood stasis type， can relieve angina pectoris symptoms and improve blood lipid indexes.