Clinical Study on Differences of Gastric Receptivity and Emptying Function of Functional Dyspepsia Patients with Different Syndromes

OBJECTIVE To study the differences of gastric receptivity and emptying function of functional dyspepsia (FD) patients with different syndromes by liquid nutrient load test combined with B ultrasound examination. METHODS Seventy four subjects were included， which included 14 healthy cases (HS group)， 60 FD patients (33 cases of spleen deficiency and qi stagnation， 16 cases of spleen deficiency and dampness accumulation， 11 cases of spleen yang deficiency). Liquid nutrient loading test was performed for all subjects， and the threshold and maximum intake were recorded combined with VAS visual score. Gastric emptying rate and half emptying time of patients with different syndromes were compared by ultrasonic measurement. RESULTS The maximum intakes of three syndromes in FD group were lower than that in the HS group (P<0.05~0.01)， and the maximum intake of spleen deficiency and dampness accumulation syndrome was lower than those of spleen deficiency and qi stagnation syndrome and spleen yang syndrome (P<0.05). Compared three syndromes in FD group with HS group， distal gastric emptying rate of postprandial 90min of spleen yang deficiency syndrome was lower than that of HS group (P<0.05). distal gastric emptying time of spleen deficiency and dampness accumulation syndrome was longer than that of spleen deficiency and qi stagnation syndrome and spleen yang deficiency syndrome in HS group (P<0.05). CONCLUSIONS There is difference in gastrointestinal motility between FD patients with the same syndrome， and that of the patients with spleen deficiency and dampness accumulation syndrome decreased more significant， which provides theoretical basis for TCM syndrome differentiation and treatment.