Comparison among Four Different Kinds of Modified "Simiao Powder" in Their Anti-gout Effect
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Graphical Abstract
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Abstract
OBJECTIVE To compare among four different kinds of modified "Simiao Powder" in their effect in inhibiting swelling of rats induced by MSU and acute toxicity.METHOD Rat swelling models were made induced by MSU in order to observe the anti-inflammatory effect of modified "Simiao Powder".RESULT Prescription A turned out to be most effective and rapid in its inhibiting effect, with long durations.The dosage of prescription A was 126 times that of the dosage of MTD and no marked acute toxic effect was found.CONCLUSION Among the four prescriptions, prescription A has the most marked anti-inflammatory effect with low toxic response.
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