Exploring the Pathogenesis and Prevention Strategies for Recurrence and Metastasis of Ovarian Cancer after Cytoreductive Surgery from the Perspective of "Impairment of Chong-Ren Meridians and Retention of Cancer-Toxin"
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Graphical Abstract
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Abstract
Given the high recurrence and mortality rates following cytoreductive surgery for ovarian cancer, Professor Wu Mianhua, a nationally renowned (traditional Chinese medicine) TCM expert, proposed that the core pathogenesis of ovarian cancer after cytoreductive surgery lies in the impairment of the Chong-Ren meridians and retention of Cancer-Toxin. Damage to Chong-Ren meridians is the root cause, and residual cancer toxins are the key. Syndrome differentiation is always based on the deficiency of the root and the excess of the symptoms. In view of the above pathogenesis, the basic treatment method of "regulating Chong-Ren meridians, dissipating turbidity and detoxifying" is established. Harmonizing Chong-Ren meridians consolidates the root, and the treatment is based on methods such as tonifying the kidney and strengthening the spleen, nourishing blood and soothing the liver; dissipating turbidity and detoxifying treats the symptoms, and the corresponding methods, such as removing stasis, draining dampness, and resolving phlegm, are used throughout. Clinical application should be tailored based on the roots and symptoms, the degree of urgency, and the characteristics of the syndromes.
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