Analysis of the Chemical Compositions of Olibanum of Different Origins Based on UPLC-Q/TOF-MS Combined with Multivariate Statistics Methods

OBJECTIVE To analyze the differential chemical composition of Olibanum of different origins and to provide some references for the identification of Olibanum origin and the quality standards.

METHODS The chemical compositions of Olibanum were analyzed by UPLC-Q/TOF-MS. Multivariate statistical methods were used to analyze Olibanum and processed products to screen the differential compounds in Olibanum of different origins.

RESULTS Using positive and negative ion scanning modes, a total of 108 compounds were identified in Olibanum. The compounds were mainly terpenes, among which triterpenes were the highest. And through multivariate statistical analysis, it was found that there were significant differences in the chemical compositions of Olibanum of different regions, with a total of 34 differential compounds; furthermore, specific compounds unique to Olibanum from other sources were identified.

CONCLUSION Different regions of Olibanum could be distinguished based on their differential chemical compositions. This study could serve as a basis for identifying different origins of Olibanum, and also provide experimental data for subsequent research on the pharmacological substance basis of Olibanum.