Discussion on Clinical Application of Bitter-Cold Medicine Based on Intestinal Flora

Bitter-cold medicine is commonly used in clinical practice and is widely used in internal medicine， surgery， gynecology， and pediatrics diseases. The homeostasis and imbalance of intestinal flora are the internal factors for curing and causing diseases. Previous researches on the clinical application of bitter-cold medicine have mostly focused on the basic research of gastrointestinal motility and hormones， No in-depth research and elaboration have been reported on the intestinal flora. From the microscopics of the structure proportion and distribution of intestinal flora， We expound the function restore of spleen and stomach by bitter-cold medicine， further prove the importance of intestinal flora in treating digestive diseases and provide more theoretical basis for clinical practices and basic experiments.