ZHANGYuan, LUOLing, TAOJin. Clinical Effect of Yangyin Tianjing Huayu Mixture on Cancer Patients with Cachexia[J]. Journal of Nanjing University of traditional Chinese Medicine, 2018, 34(6): 561-564.
Citation: ZHANGYuan, LUOLing, TAOJin. Clinical Effect of Yangyin Tianjing Huayu Mixture on Cancer Patients with Cachexia[J]. Journal of Nanjing University of traditional Chinese Medicine, 2018, 34(6): 561-564.

Clinical Effect of Yangyin Tianjing Huayu Mixture on Cancer Patients with Cachexia

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  • OBJECTIVE To observe the clinical effect of Yangyin Tianjing Huayu Mixture on cancer patients with yin deficiency and blood stasis syndrome of cancer cachexia. METHODS According to the method of single blind randomized controlled trial, 100 patients with advanced tumor were individed into two groups, the treatment group was treated with Yangyin Tianjin Huayu Mixture, the control group was treated with medroxyprogesterone acetate. Both groups were given nutritional support and symptomatic treatment. The changes of TCM syndrome score, quality of life score and laboratory indexes of two groups were observed. RESULTS The difference of TCM syndrome therapeutic effect between treatment group and control group was statistically significant (P<0.05), and the total effective rate was 46%, superior to that of the control group(P<0.01). The difference of life quality score and the difference of TCM syndrome index score between the two groups were statistically significant. In terms of laboratory test results, the difference of hemoglobin, prealbumin and serum albumin between the treatment group and the control group was statistically significant. CONCLUSION Yangyin Tianjing Huayu Mixture can effectively improve the quality of life of the patients with yin deficiency blood stasis syndrome of cancer cachexia and significantly improve the level of hemoglobin, prealbumin and serum albumin.
  • [1]
    吴国豪.癌性恶病质发生机制及防治对策[J].中国实用外科杂志,2015,35(1): 36-39.
    [2]
    梁翠微,杨兵,杜均祥,等.晚期肺癌恶病质中医辨证分型及细胞因子变化[J].安徽中医学院学报,2010,29(6): 33-35.
    [3]
    王晓星,涂元宝,刘贤亮,等.滋阴活血方治疗IgA肾病阴虚血瘀证60例[J].安徽中医药大学学报,2014,33(4): 38-41.
    [4]
    马丽虹,李可建.中风阴虚血瘀生风病机假说的循证检验研究[J].山东中医药大学学报,2014,38(6): 515-516.
    [5]
    严倩华,余江毅.中西医结合治疗2型糖尿病阴虚血瘀证85例观察[J].实用中医药杂志,2015,31(3): 219-220.
    [6]
    高文斌,王若雨,梁文波.肿瘤并发症的诊断与治疗[M].北京:人民军医出版社,2009:173-176.
    [7]
    中药新药临床研究指导原则(试行)[M].中国医药科技出版社,2002:86-89.
    [8]
    国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:203-206.
    [9]
    万崇华,陈明清,张灿珍,等.癌症患者生命质量测定量表EORTC QLQ-C30中文版评价[J].实用肿瘤杂志,1997,17(5):263-265.
    [10]
    FEARON K, ARENDS J, BARACOS V. Understanding the mechanisms and treatment options in cancer cachexia[J]. Nat Rev Clin Oncol, 2013, 10(2): 90-99.
    [11]
    苏雅,祝永福,夏黎明,等.中医辨证治疗癌症恶病质临床疗效观察[J].中医药临床杂志,2015,29(9): 1251-1254.
    [12]
    张玉红.和胃汤治疗癌症食欲不振恶病质综合征的临床观察[D].北京:北京中医药大学,2015.
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